A three-year-old male neutered Labrador retriever from the Ohio river valley basin is presented with chronic large bowel diarrhea and signs of respiratory disease (cough, fever).
A lymph node smear shows round to ovoid (1-4 micrometers) encapsulated structures inside macrophages and giant cells. The organisms have thin cell walls, with thin clear zone between cell wall and cytoplasm.
What is the diagnosis?
A - Cryptococcosis
B - Coccidioidomycosis
C - Blastomycosis
D - Histoplasmosis
E - Aspergillosis
answer/D